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Exercise and cognition

The effect of resistance training on cognitive function, cortical plasticity and falls risk in older women aged 65 to 75 years: A 1 year randomized controlled trial.


Project Goals - What are we doing?

We will ascertain whether a one-year, twice-weekly resistance training program significantly ameliorates cognitive performance of executive-controlled processes in community-dwelling, cognitively-intact women aged 65 to 75 years old compared with a one-year, twice-weekly stretch and relax program.

Research Outcomes - What will be achieved?

The results of this study will help to define what types of exercise should be "prescribed" for at-risk, older adults to enhance cognitive function and to decrease the risk of falling.

Background - Why is this research important?

According to the 1994 Canadian Study of Health and Aging, cognitive impairment of all types increases with age and affects 65% of those Canadians aged 85 years and older. Falls are the most frequent cause of injury-related morbidity and mortality among older people. Cognitive impairment is a leading fall risk factor. Approximately 60% of older adults with cognitive impairment, with or without dementia, fall annually; this incidence is approximately twice that of cognitively normal peers. The cognitively impaired older faller is also at increased risk of major injury such as fracture. Thus, interventions that either prevent the onset of cognitive impairment or prevent further cognitive decline in the aging population are likely to reduce falls and fall-related fractures. Recent evidence suggests physical activity, specifically cardiovascular fitness training (CVT), has benefits for cognition in older adults. However, few studies to date have examined the effect of other types of exercises, such as resistance training on cognitive function in older adults.


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Project Team

Principal Investigator:

Teresa Liu-Ambrose, PhD
Assistant Professor Department of Physical Therapy, UBC Brain Research Centre Centre for Hip Health


Co-Investigators:

Maureen Ashe, PhD
Lynn Beattie, MD, FRCPC
Peter Graf, PhD
Todd Handy, PhD

Research Expertise:

Falls Prevention, Exercise Prescription, Bone Health

Contact Information:

357-2647 Willow Street
Vancouver, BC, V5Z 1L8
teresa.ambrose@vch.ca
604-875-4111 EXT 62095

Funding Support:

Vancouver Foundation - BC Medical Services Foundation
Michael Smith Foundation for Health Research